How modelling can help steer the course set by the World Health Organization 2021-2030 roadmap on neglected tropical diseases

Clark, J. et al. (2022) How modelling can help steer the course set by the World Health Organization 2021-2030 roadmap on neglected tropical diseases. Gates Open Research, 5, 112. (doi: 10.12688/gatesopenres.13327.2) (PMID:35169682) (PMCID:PMC8816801)

Abstract

The World Health Organization recently launched its 2021-2030 roadmap, Ending the Neglect to Attain the Sustainable Development Goals, an updated call to arms to end the suffering caused by neglected tropical diseases. Modelling and quantitative analyses played a significant role in forming these latest goals. In this collection, we discuss the insights, the resulting recommendations and identified challenges of public health modelling for 13 of the target diseases: Chagas disease, dengue, gambiense human African trypanosomiasis (gHAT), lymphatic filariasis (LF), onchocerciasis, rabies, scabies, schistosomiasis, soil-transmitted helminthiases (STH), Taenia solium taeniasis/ cysticercosis, trachoma, visceral leishmaniasis (VL) and yaws. This piece reflects the three cross-cutting themes identified across the collection, regarding the contribution that modelling can make to timelines, programme design, drug development and clinical trials.

• Item Type: Articles
• Additional Information: This work was supported by the Bill and Melinda Gates Foundation through the Neglected Tropical Disease (NTD) Modelling Consortium (OPP1184344). JT acknowledges funding from the Medical Research Council (MRC) Centre for Global Infectious Disease Analysis (reference MR/R015600/1), jointly funded by the UK MRC and the UK Foreign, Commonwealth & Development Office (FCDO), under the MRC/FCDO Concordat agreement and is also part of the European and Developing Countries Clinical Trials Partnership (EDCTP2) programme supported by the European Union. MGB and MAD acknowledge joint centre funding (grant No. MR/R015600/1) by the UK MRC and the UK Department for International Development (DFID) under the MRC/DFID Concordat agreement which is also part of the EDCTP2 programme supported by the European Union.
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Clark, Dr Jessica and Hampson, Professor Katie

Creator Roles

Clark, J.: Conceptualization, Writing – original draft, Writing – review and editing
Hampson, K.: Writing – original draft, Writing – review and editing

• Authors: Clark, J., Stolk, W. A., Basáñez, M.-G., Coffeng, L. E., Cucunubá, Z. M., Dixon, M. A., Dyson, L., Hampson, K., Marks, M., Medley, G. F., Pollington, T. M., Prada, J. M., Rock, K. S., Salje, H., Toor, J., and Hollingsworth, T. D.
• College/School: College of Medical Veterinary and Life Sciences > School of Biodiversity, One Health & Veterinary Medicine
• Journal Name: Gates Open Research
• Publisher: F1000Research
• ISSN: 2572-4754
• ISSN (Online): 2572-4754
• Published Online: 27 July 2021
• Copyright Holders: Copyright © 2022 Clark J et al.
• First Published: First published in Gates Open Research 5: 112
• Publisher Policy: Reproduced under a Creative Commons License