Gaglianese, A., Fracasso, A. , Fernandes, F. G., Harvey, B., Dumoulin, S. O. and Petridou, N. (2023) Mechanisms of speed encoding in the human middle temporal cortex measured by 7T fMRI. Human Brain Mapping, 44(5), pp. 2050-2061. (doi: 10.1002/hbm.26193) (PMID:36637226) (PMCID:PMC9980888)
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Abstract
Perception of dynamic scenes in our environment results from the evaluation of visual features such as the fundamental spatial and temporal frequency components of a moving object. The ratio between these two components represents the object's speed of motion. The human middle temporal cortex hMT+ has a crucial biological role in the direct encoding of object speed. However, the link between hMT+ speed encoding and the spatiotemporal frequency components of a moving object is still under explored. Here, we recorded high resolution 7T blood oxygen level‐dependent BOLD responses to different visual motion stimuli as a function of their fundamental spatial and temporal frequency components. We fitted each hMT+ BOLD response with a 2D Gaussian model allowing for two different speed encoding mechanisms: (1) distinct and independent selectivity for the spatial and temporal frequencies of the visual motion stimuli; (2) pure tuning for the speed of motion. We show that both mechanisms occur but in different neuronal groups within hMT+, with the largest subregion of the complex showing separable tuning for the spatial and temporal frequency of the visual stimuli. Both mechanisms were highly reproducible within participants, reconciling single cell recordings from MT in animals that have showed both encoding mechanisms. Our findings confirm that a more complex process is involved in the perception of speed than initially thought and suggest that hMT+ plays a primary role in the evaluation of the spatial features of the moving visual input.
| Item Type: | Articles |
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| Additional Information: | This work was supported by the Netherlands Organization for Scientific Research (NWO), Vidi Grant number 13339 (Natalia Petridou) and by the National Institute Of Mental Health of the National Institutes of Health under Award Number R01MH111417. Alessio Fracasso is supported by a grant from the Biotechnology and Biology research council (BBSRC, grant number: BB/S006605/1) and the Fundacao Bial, Fundacao Bial Grants Programme 2020/21, A-29315, number 203/2020, grant edition: G-15516. Ben Harvey is supported by the Netherlands Organization for Scientific Research (NWO), Vidi Grant number 452.17.012 to Ben Harvey. This work was also supported by Marie Curie program grant funded to Anna Gaglianese, grant number DLV-894612. |
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Fracasso, Dr Alessio |
| Authors: | Gaglianese, A., Fracasso, A., Fernandes, F. G., Harvey, B., Dumoulin, S. O., and Petridou, N. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Psychology & Neuroscience |
| Journal Name: | Human Brain Mapping |
| Publisher: | Wiley |
| ISSN: | 1065-9471 |
| ISSN (Online): | 1097-0193 |
| Published Online: | 13 January 2023 |
| Copyright Holders: | Copyright © 2023 The Authors |
| First Published: | First published in Human Brain Mapping 44(5): 2050-2061 |
| Publisher Policy: | Reproduced under a Creative Commons License |
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