Cabasag, C. J. et al. (2023) Shifting incidence and survival of epithelial ovarian cancer (1995‐2014): a SurvMark ‐2 study. International Journal of Cancer, 152(9), pp. 1763-1777. (doi: 10.1002/ijc.34403) (PMID:36533660)
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Abstract
The aim of the study is to provide a comprehensive assessment of incidence and survival trends of epithelial ovarian cancer (EOC) by histological subtype across seven high income countries (Australia, Canada, Denmark, Ireland, New Zealand, Norway, and the United Kingdom). Data on invasive EOC diagnosed in women aged 15-99 years during 1995-2014 were obtained from 20 cancer registries. Age standardized incidence rates and average annual percentage change were calculated by subtype for all ages and age groups (15-64 and 65-99 years). Net survival (NS) was estimated by subtype, age group, and 5-year period using Pohar-Perme estimator. Our findings showed marked increase in serous carcinoma incidence was observed between 1995-2014 among women aged 65-99 years with average annual increase ranging between 2.2% and 5.8%. We documented a marked decrease in the incidence of adenocarcinoma ‘not otherwise specified’ with estimates ranging between 4.4% and 7.4% in women aged 15-64 years and between 2.0% and 3.7% among the older age group. Improved survival, combining all EOC subtypes, was observed for all ages combined over the 20-year study period in all countries with 5-year NS absolute percent change ranging between 5.0 in Canada and 12.6 in Denmark. Several factors such as changes in guidelines and advancement in diagnostic tools may potentially influence the observed shift in histological subtypes and temporal trends. Progress in clinical management and treatment over the past decades potentially plays a role in the observed improvements in EOC survival.
| Item Type: | Articles |
|---|---|
| Additional Information: | ICBP is funded by the Canadian Partnership Against Cancer; Cancer Council Victoria; Cancer Institute NSW; Cancer Research UK; Danish Cancer Society; National Cancer Registry Ireland; The Cancer Society of New Zealand; NHS England; Norwegian Cancer Society; Public Health Agency Northern Ireland on behalf of the Northern Ireland Cancer Registry; DG Health and Social Care, Scottish Government; Western Australia Department of Health; Public Health Wales NHS Trust. |
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Morrison, Dr David |
| Creator Roles: | |
| Authors: | Cabasag, C. J., Arnold, M., Rutherford, M., Ferlay, J., Bardot, A., Morgan, E., Butler, J., O'Connell, D. L., Nelson, G., Høgdall, C., Schnack, T., Gavin, A., Elwood, M., Hanna, L., Gourley, C., De, P., Saint‐Jacques, N., Mørch, L. S., Woods, R. R., Altman, A. D., Sykes, P., Cohen, P. A., McNally, O., Møller, B., Walsh, P., Morrison, D. S., Bray, F., and Soerjomataram, I. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Health & Wellbeing > General Practice and Primary Care |
| Journal Name: | International Journal of Cancer |
| Publisher: | Wiley |
| ISSN: | 0020-7136 |
| ISSN (Online): | 1097-0215 |
| Published Online: | 19 December 2022 |
| Copyright Holders: | Copyright © 2022 International Agency for Research on Cancer |
| First Published: | First published in International Journal of Cancer 152(9): 1763-1777 |
| Publisher Policy: | Reproduced in accordance with the copyright policy of the publisher |
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