A Multi-Parametric Finite Element Analysis of Heat Distributions in Implanted Micro-LEDs

Walton, F. , Cerezo-Sanchez, M., Ge, C. and Heidari, H. (2022) A Multi-Parametric Finite Element Analysis of Heat Distributions in Implanted Micro-LEDs. In: 29th IEEE International Conference on Electronics, Circuits and Systems (ICECS 2022), Glasgow, UK, 24-26 October 2022, ISBN 9781665488235 (doi: 10.1109/ICECS202256217.2022.9970997)

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Optogenetics is a breakthrough neurostimulation technology which enables precise optical control over the function of neurons that have been genetically engineered to feature light-sensitive opsin proteins. With notable exceptions, the light source is typically placed externally, and light is guided in via optical fibres. This is advantageous because the light source is less constrained in terms of size, power and heat generation. This comes at the disadvantage of needing a permanent hole in the blood brain barrier so efforts to fully implant the light source, with wireless communication and power are needed. Here we present a multi-parametric finite element analysis of the heat distribution generated by typical micro-light emitting diodes in optical implants, encapsulated by a polymer. Our simulation results have elucidated the relationships between the temperature rise at the device/tissue interface and irradiance, encapsulation thickness and time.

Item Type:Conference Proceedings
Additional Information:This work was partially supported by the European Union’s Horizon 2020 Hybrid Enhanced Regenerative Medicine Systems (HERMES) project (GA no. 824164). F.W. is supported by the Engineering and Physical Sciences Research Council (EPSRC) Doctoral Prize Research Fellowship ‘Scalable Controlled Treatment impLAntables for Neurological Disorders’ (SCOTLAND) under Grant no. EP/T517896/1, the EPSRC Impact Acceleration Account ProtoFlex, no. EP/R511705/1. M.C.-S. and C. G. are supported by HERMES.
Glasgow Author(s) Enlighten ID:Walton, Mr Finlay and Ge, Changhao and Cerezo Sanchez, Maria and Heidari, Professor Hadi
Authors: Walton, F., Cerezo-Sanchez, M., Ge, C., and Heidari, H.
College/School:College of Science and Engineering > School of Engineering > Electronics and Nanoscale Engineering
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