Smart green CQD@SiO2 hybrid coated optical fiber manifesting dual versatile absorptive and MIP features towards epinephrine detection

Azargoshasb, T., Parvizi, R., Bozorgzadeh, F., Navid, H. A. and Heidari, H. (2023) Smart green CQD@SiO2 hybrid coated optical fiber manifesting dual versatile absorptive and MIP features towards epinephrine detection. Nanoscale Advances, 5(2), pp. 459-470. (doi: 10.1039/D2NA00687A)

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Abstract

For the first time, in this study, a novel optical fiber biosensor is proposed and developed via coating only one smart functional layer of silica-supported carbon dots realizing the concepts of both lossy mode resonance (LMR) and molecularly imprinted polymer (MIP) for epinephrine detection. The carbon quantum dots (CQDs) are prepared using a green synthesis method and then treated with a molecularly imprinted polymer (MIP) strategy. Under ultrasonic irradiation, a SiO2 shell was stabilized on the surface of the CQDs to graft and to provide the LMR/MIP functional layer onto the curved optical fiber surface. Accurate structural and morphological characterization confirmed the carbon quantum dot agents and also the SiO2 supporting shells on the optical fiber, while spectroscopic analysis confirms the formation of the imprinted polymer and desirable absorbance characteristics. The experimental and numerical sensing studies revealed that the proposed sensing probe allows the rapid adsorption/desorption of epinephrine to the sensing films and highly permeable coating for studying the influence of effective parameters. Under the optimal experimental conditions, the sensitivity of the proposed LMR-based optical fiber sensor is reported to be 0.37 nm μM−1 with a correlation coefficient of 0.99. So, sensitive detection of epinephrine at a low concentration can be guaranteed with a 0.72 mM LOD.

Item Type:Articles
Additional Information:This work was partially supported by British Council Innovative and Collaborative Research Partnerships Grants, (FleEnSys project ICRG 165) and EPSRC Industrial CASE (EP/ W522168/1).
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Parvizi, Dr Roghaieh and Heidari, Professor Hadi
Authors: Azargoshasb, T., Parvizi, R., Bozorgzadeh, F., Navid, H. A., and Heidari, H.
College/School:College of Science and Engineering > School of Engineering > Electronics and Nanoscale Engineering
Journal Name:Nanoscale Advances
Publisher:Royal Society of Chemistry
ISSN:2516-0230
ISSN (Online):2516-0230
Published Online:19 December 2022
Copyright Holders:Copyright © 2023 The Authors
First Published:First published in American Journal of Mathematics 5(2): 459-470
Publisher Policy:Reproduced under a Creative Commons licence

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