Bianciardi, B., Gajwani, R. , Gross, J. , Gumley, A. I. , Lawrie, S. M., Moelling, M., Schwannauer, M., Schultze-Lutter, F., Fracasso, A. and Uhlhaas, P. J. (2023) Investigating temporal and prosodic markers in clinical high-risk for psychosis participants using automated acoustic analysis. Early Intervention in Psychiatry, 17(3), pp. 327-330. (doi: 10.1111/eip.13357) (PMID:36205386)
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Abstract
Aim Language disturbances are a candidate biomarker for the early detection of psychosis. Temporal and prosodic abnormalities have been observed in schizophrenia patients, while there is conflicting evidence whether such deficits are present in participants meeting clinical high-risk for psychosis (CHR-P) criteria. Methods Clinical interviews from CHR-P participants (n = 50) were examined for temporal and prosodic metrics and compared against a group of healthy controls (n = 17) and participants with affective disorders and substance abuse (n = 23). Results There were no deficits in acoustic variables in the CHR-P group, while participants with affective disorders/substance abuse were characterized by slower speech rate, longer pauses and higher unvoiced frames percentage. Conclusion Our finding suggests that temporal and prosodic aspects of speech are not impaired in early-stage psychosis. Further studies are required to clarify whether such abnormalities are present in sub-groups of CHR-P participants with elevated psychosis-risk.
| Item Type: | Articles |
|---|---|
| Additional Information: | This study was supported by project MR/L011689/1 from the Medical Research Council (MRC). We acknowledge the support of the Scottish Mental Health Research Network (http://www.smhrn.org.uk), now called the NHS Research Scotland Mental Health Network (NRS MHN: http://www.nhsresearchscotland.org.uk/research-areas/mental-health), for providing assistance with participant recruitment, interviews and cognitive assessments. We would like to thank both the participants and patients who took part in the study and the research assistants of the YouR-study for supporting the recruitment and assessment of CHR-P participants. AF is supported by a grant from the Biotechnology and Biology Research Council (BBSRC, grant number BBS00/6605/1) and the Bial Foundation (grant id: A-29315, n. 203/2020, grant edition: G1-5516). |
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Uhlhaas, Professor Peter and Gross, Professor Joachim and Gumley, Professor Andrew and Fracasso, Dr Alessio and Gajwani, Dr Ruchika and Bianciardi, Miss Bianca |
| Authors: | Bianciardi, B., Gajwani, R., Gross, J., Gumley, A. I., Lawrie, S. M., Moelling, M., Schwannauer, M., Schultze-Lutter, F., Fracasso, A., and Uhlhaas, P. J. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Health & Wellbeing > Mental Health and Wellbeing College of Medical Veterinary and Life Sciences > School of Psychology & Neuroscience |
| Journal Name: | Early Intervention in Psychiatry |
| Publisher: | Wiley |
| ISSN: | 1751-7885 |
| ISSN (Online): | 1751-7893 |
| Published Online: | 07 October 2022 |
| Copyright Holders: | Copyright © 2022 The Authors |
| First Published: | First published in Early Intervention in Psychiatry 17(3):327-330 |
| Publisher Policy: | Reproduced under a Creative Commons License |
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