Emulation of cardiac mechanics using Graph Neural Networks

Dalton, D., Gao, H. and Husmeier, D. (2022) Emulation of cardiac mechanics using Graph Neural Networks. Computer Methods in Applied Mechanics and Engineering, 401(B), 115645. (doi: 10.1016/j.cma.2022.115645)

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Abstract

Recent progress in Graph Neural Networks (GNNs) has allowed the creation of new methods for surrogate modelling, or emulation, of complex physical systems to a high level of fidelity. The success of such methods has yet to be explored however in the context of soft-tissue mechanics, an area of research which has itself seen substantial developments in recent years. The present work explicates on this by introducing an emulation framework based on a multi-scale, message-passing GNN, before applying it to the modelling of passive left-ventricle mechanics. Through numerical experiments, it is demonstrated that the proposed method delivers strong predictive accuracy when benchmarked against the results of the nonlinear finite-element method (FEM), and significantly outperforms an alternative emulator based on a fully connected neural network. Furthermore, large computational gains are achieved at prediction time against the FEM.

Item Type:Articles
Additional Information:This work as funded by the Engineering and Physical Sciences Research Council (EPSRC) of the United Kingdom, grant reference numbers EP/T017899/1, EP/S030875/1 and EP/S020950/1.
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Dalton, David and Gao, Dr Hao and Husmeier, Professor Dirk
Authors: Dalton, D., Gao, H., and Husmeier, D.
College/School:College of Science and Engineering
College of Science and Engineering > School of Mathematics and Statistics > Statistics
Journal Name:Computer Methods in Applied Mechanics and Engineering
Publisher:Elsevier
ISSN:0045-7825
ISSN (Online):1879-2138
Published Online:06 October 2022
Copyright Holders:Copyright © 2022 The Authors
First Published:First published in Computer Methods in Applied Mechanics and Engineering 401(B):115645
Publisher Policy:Reproduced under a Creative Commons licence

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
308255The SofTMech Statistical Emulation and Translation HubDirk HusmeierEngineering and Physical Sciences Research Council (EPSRC)EP/T017899/1M&S - Statistics
303232EPSRC Centre for Multiscale soft tissue mechanics with MIT and POLIMI (SofTMech-MP)Xiaoyu LuoEngineering and Physical Sciences Research Council (EPSRC)EP/S030875/1M&S - Mathematics
303231A whole-heart model of multiscale soft tissue mechanics and fluid structureinteraction for clinical applications (Whole-Heart-FSI)Xiaoyu LuoEngineering and Physical Sciences Research Council (EPSRC)EP/S020950/1M&S - Mathematics