De Glanville, W. A. et al. (2022) An outbreak of Rift Valley fever among peri-urban dairy cattle in northern Tanzania. Transactions of the Royal Society of Tropical Medicine and Hygiene, 116(11), pp. 1082-1090. (doi: 10.1093/trstmh/trac076) (PMID:36040309) (PMCID:PMC9623736)
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Abstract
Background: Human and animal cases of Rift Valley fever (RVF) are typically only reported during large outbreaks. The occurrence of RVF cases that go undetected by national surveillance systems in the period between these outbreaks is considered likely. The last reported cases of RVF in Tanzania occurred during a large outbreak in 2007–2008. Methods: Samples collected between 2017 and 2019 from livestock suffering abortion across northern Tanzania were retrospectively tested for evidence of RVF virus infection using serology and reverse transcription quantitative polymerase chain reaction (RT-qPCR). Results: A total of 14 RVF-associated cattle abortions were identified among dairy cattle in a peri-urban area surrounding the town of Moshi. RVF cases occurred from May to August 2018 and were considered to represent an undetected, small-scale RVF outbreak. Milk samples from 3 of 14 cases (21%) were found to be RT-qPCR positive. Genotyping revealed circulation of RVF viruses from two distinct lineages. Conclusions: RVF outbreaks can occur more often in endemic settings than would be expected on the basis of detection by national surveillance. The occurrence of RVF cases among peri-urban dairy cattle and evidence for viral shedding in milk, also highlights potentially emerging risks for RVF associated with increasing urban and peri-urban livestock populations.
| Item Type: | Articles |
|---|---|
| Additional Information: | This research was supported by the Supporting Evidence Based Interventions project, University of Edinburgh (R83537) and the Zoonoses and Emerging Livestock Systems program (funded through the Biotechnology and Biological Sciences Research Council, Department for International Development, Economic and Social Research Council, Medical Research Council, Natural Environment Research Council and Defence Science and Technology Laboratory; BB/L018926/1, BB/L017679/1, BB/N503563/1). Additional financial support was provided through the Biotechnology and Biological Sciences Research Council (BB/J010367) and the National Institutes of Health (R01TW009237). |
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | De Glanville, Dr William and Halliday, Dr Jo and Lankester, Dr Felix and MMBAGA, Professor Blandina Theoph and Willett, Professor Brian and Ladbury, Georgia Ann Frances and Rostal, Melinda Kathleen and Allan, Dr Kathryn and Brennan, Dr Benjamin and Cleaveland, Professor Sarah and Carter, Mr Ryan and Claxton, Dr John and Szemiel, Dr Agnieszka |
| Authors: | De Glanville, W. A., Allan, K., Nyarobi, J. M., Thomas, K. M., Lankester, F., Kibona, T. J., Claxton, J. R., Brennan, B., Carter, R., Crump, J. A., Halliday, J. E.B., Ladbury, G., MMBAGA, B. T., Mramba, F., Nyasebwa, O. M., Rubach, M. P., Rostal, M. K., Sanka, P., Swai, E. S., Szemiel, A. M., Willett, B. J., and Cleaveland, S. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Biodiversity, One Health & Veterinary Medicine College of Medical Veterinary and Life Sciences > School of Health & Wellbeing > General Practice and Primary Care College of Medical Veterinary and Life Sciences > School of Infection & Immunity College of Medical Veterinary and Life Sciences > School of Infection & Immunity > Centre for Virus Research |
| Journal Name: | Transactions of the Royal Society of Tropical Medicine and Hygiene |
| Publisher: | Oxford University Press |
| ISSN: | 0035-9203 |
| ISSN (Online): | 1878-3503 |
| Published Online: | 30 August 2022 |
| Copyright Holders: | Copyright © 2022 The Authors |
| First Published: | First published in Transactions of the Royal Society of Tropical Medicine and Hygiene 116(11): 1082-1090 |
| Publisher Policy: | Reproduced under a Creative Commons license |
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