Infravec2 guidelines for the design and operation of containment level 2 and 3 insectaries in Europe

Pondeville, E. et al. (2023) Infravec2 guidelines for the design and operation of containment level 2 and 3 insectaries in Europe. Pathogens and Global Health, 117(3), pp. 293-307. (doi: 10.1080/20477724.2022.2108639) (PMID:35996820) (PMCID:PMC10081053)

Abstract

With the current expansion of vector-based research and an increasing number of facilities rearing arthropod vectors and infecting them with pathogens, common measures for containment of arthropods as well as manipulation of pathogens are becoming essential for the design and running of such research facilities to ensure safe work and reproducibility, without compromising experimental feasibility. These guidelines and comments were written by experts of the Infravec2 consortium, a Horizon 2020-funded consortium integrating the most sophisticated European infrastructures for research on arthropod vectors of human and animal diseases. They reflect current good practice across European laboratories with experience of safely handling different mosquito species and the pathogens they transmit. As such, they provide experience-based advice to assess and manage the risks to work safely with mosquitoes and the pathogens they transmit. This document can also form the basis for research with other arthropods, for example, midges, ticks or sandflies, with some modification to reflect specific requirements.

• Item Type: Articles
• Additional Information: This work was supported by the European Union’s Horizon 2020 research and innovation programme under grant agreement No 731060; the UK Medical Research Council to AK and EP under grant Medical Research Council (MRC) MC_UU_12014/8; the ANR to ABF under grant n° ANR-10-LABX-62-IBEID; the CERCA Programme., Generalitat de Catalunya to NB and FXA; the ERD funds CZ.02.1.01/0.0/0.0/16_019/0000759 to PV under grant CZ.02.1.01/0.0/0.0/16_019/000075.
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Pondeville, Dr Emilie and Wilson, Dr Anthony James and Kohl, Professor Alain
• Authors: Pondeville, E., Failloux, A.-B., Simard, F., Volf, P., Cristanti, A., Haghighat-Khah, R. E., Busquets, N., Abad, F. X., Wilson, A. J., Bellini, R., Marsh Arnaud, S., Kohl, A., and Veronesi, E.
• College/School: College of Medical Veterinary and Life Sciences > School of Biodiversity, One Health & Veterinary Medicine; College of Medical Veterinary and Life Sciences > School of Infection & Immunity > Centre for Virus Research
• Journal Name: Pathogens and Global Health
• Publisher: Taylor and Francis
• ISSN: 2047-7724
• ISSN (Online): 2047-7732
• Published Online: 22 August 2022
• Copyright Holders: Copyright © 2022 The Authors
• First Published: First published in Pathogens and Global Health 117(3): 293-307
• Publisher Policy: Reproduced under a Creative Commons license

Project Code	Award No	Project Name	Principal Investigator	Funder's Name	Funder Ref	Lead Dept
173819		INFRAVEC-2	Alain Kohl	European Commission (EC)	Kohl, Dr Alain	III-MRC-GU Centre for Virus Research
172630007		Arthropod-borne infections and emerging virus infections in high risk areas (Programme 4)	Alain Kohl	Medical Research Council (MRC)	MC_UU_12014/8	III - Centre for Virus Research