Morris, E. P. and da Fonseca, P. C.A. (2021) How to build a proteasome. Nature Structural and Molecular Biology, 28(5), pp. 409-410. (doi: 10.1038/s41594-021-00592-8)
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Abstract
The biogenesis of eukaryotic 20S proteasomes requires the accurate assembly of 14 closely related protein subunits and occurs in a complex series of chaperone-dependent steps. Important insights into this pathway are now provided by the high-resolution cryo-EM structures of two 20S proteasome assembly intermediates.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | da Fonseca, Professor Paula and Morris, Dr Edward |
| Authors: | Morris, E. P., and da Fonseca, P. C.A. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Molecular Biosciences |
| Journal Name: | Nature Structural and Molecular Biology |
| Publisher: | Nature Research |
| ISSN: | 1545-9993 |
| ISSN (Online): | 1545-9985 |
| Published Online: | 29 April 2021 |
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