Grinberg, A., Lopez-Villalobos, N., Pomroy, W., Widmer, G., Smith, H. and Tait, A. (2008) Host-shaped segregation of the Cryptosporidium parvum multilocus genotype repertoire. Epidemiology and Infection, 136(2), pp. 273-278. (doi: 10.1017/S0950268807008345)
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Abstract
Cattle are among the major reservoirs of Cryptosporidium parvum in nature. However, the relative contribution of C. parvum oocysts originating from cattle to human disease burden is difficult to assess, as various transmission pathways – including the human to human route – can co-occur. In this study, multilocus genotype richness of representative samples of human and bovine C. parvum are compared statistically using analytical rarefaction and non-parametric taxonomic richness estimators. Results suggest that in the time and space frames underlying the analysed data, humans were infected with significantly wider spectra of C. parvum genotypes than cattle, and consequently, a significant fraction of human infections may not have originated from the regional bovine reservoirs. This study provides statistical support to the emerging idea of the existence of distinct anthroponotic C. parvum cycles that do not involve cattle.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Tait, Professor Andy |
| Authors: | Grinberg, A., Lopez-Villalobos, N., Pomroy, W., Widmer, G., Smith, H., and Tait, A. |
| College/School: | College of Medical Veterinary and Life Sciences |
| Journal Name: | Epidemiology and Infection |
| ISSN: | 0950-2688 |
| ISSN (Online): | 1469-4409 |
| Published Online: | 30 March 2007 |
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