Stear, M.J., Bishop, S.C., Henderson, N.G. and Scott, I. (2003) A key mechanism of pathogenesis in sheep infected with the nematode Teladorsagia circumcincta. Animal Health Research Reviews, 4(1), pp. 45-52. (doi: 10.1079/AHRR200351)
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Abstract
Infection of sheep with the abomasal nematode Teladorsagia circumcincta can cause a relative protein deficiency and reduce growth rate in growing lambs. A key event appears to be the destruction of junctions between epithelial cells. If the infection is heavy or prolonged, this leads to increased mucus production, hyperplasia, decreased acid production, gastrinemia, inappetance and pepsinogenemia. The severity of the infection depends upon the extent of concurrent infection, the nutritional status of the host and genetically controlled variation in the ability to mount protective immune responses.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Stear, Professor Mike |
| Authors: | Stear, M.J., Bishop, S.C., Henderson, N.G., and Scott, I. |
| College/School: | College of Medical Veterinary and Life Sciences College of Medical Veterinary and Life Sciences > School of Infection & Immunity |
| Journal Name: | Animal Health Research Reviews |
| ISSN: | 1466-2523 |
| ISSN (Online): | 1475-2654 |
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