Luo, Z. et al. (2022) Beta-glucan alters gut microbiota and plasma metabolites in pre-weaning dairy calves. Metabolites, 12(8), 687. (doi: 10.3390/metabo12080687) (PMID:35893252) (PMCID:PMC9332571)
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Abstract
The present study aims to evaluate the alterations in gut microbiome and plasma metabolites of dairy calves with β-glucan (BG) supplementation. Fourteen healthy newborn dairy calves with similar body weight were randomly divided into control (n = 7) and BG (n = 7) groups. All the calves were fed on the basal diet, while calves in the BG group were supplemented with oat BG on d 8 for 14 days. Serum markers, fecal microbiome, and plasma metabolites at d 21 were analyzed. The calves were weaned on d 60 and weighed. The mean weaning weight of the BG group was 4.29 kg heavier than that of the control group. Compared with the control group, the levels of serum globulin, albumin, and superoxide dismutase were increased in the BG group. Oat BG intake increased the gut microbiota richness and decreased the Firmicutes-to-Bacteroidetes ratio. Changes in serum markers were found to be correlated with the plasma metabolites, including sphingosine, trehalose, and 3-methoxy-4-hydroxyphenylglycol sulfate, and gut microbiota such as Ruminococcaceae_NK4A214, Alistipes, and Bacteroides. Overall, these results suggest that the BG promotes growth and health of pre-weaning dairy calves by affecting the interaction between the host and gut microbiota.
Item Type: | Articles |
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Additional Information: | This research was funded by the Sichuan Science and Technology Program (No. 2019YJ0671) and the Key R&D Program Supported by the Department of Science and Technology of Gansu Province (No. 20YF8NA029). |
Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Huang, Yixin |
Creator Roles: | |
Authors: | Luo, Z., Ma, L., Zhou, T., Huang, Y., Zhang, L., Du, Z., Yong, K., Yao, X., Shen, L., Yu, S., Shi, X., and Cao, S. |
College/School: | College of Medical Veterinary and Life Sciences > School of Biodiversity, One Health & Veterinary Medicine |
Journal Name: | Metabolites |
Publisher: | MDPI |
ISSN: | 2218-1989 |
ISSN (Online): | 2218-1989 |
Published Online: | 26 July 2022 |
Copyright Holders: | Copyright © 2022 The Authors |
First Published: | First published in Metabolites 12(8): 687 |
Publisher Policy: | Reproduced under a Creative Commons License |
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