Beta-glucan alters gut microbiota and plasma metabolites in pre-weaning dairy calves

Luo, Z. et al. (2022) Beta-glucan alters gut microbiota and plasma metabolites in pre-weaning dairy calves. Metabolites, 12(8), 687. (doi: 10.3390/metabo12080687) (PMID:35893252) (PMCID:PMC9332571)

[img] Text
275695.pdf - Published Version
Available under License Creative Commons Attribution.

2MB

Abstract

The present study aims to evaluate the alterations in gut microbiome and plasma metabolites of dairy calves with β-glucan (BG) supplementation. Fourteen healthy newborn dairy calves with similar body weight were randomly divided into control (n = 7) and BG (n = 7) groups. All the calves were fed on the basal diet, while calves in the BG group were supplemented with oat BG on d 8 for 14 days. Serum markers, fecal microbiome, and plasma metabolites at d 21 were analyzed. The calves were weaned on d 60 and weighed. The mean weaning weight of the BG group was 4.29 kg heavier than that of the control group. Compared with the control group, the levels of serum globulin, albumin, and superoxide dismutase were increased in the BG group. Oat BG intake increased the gut microbiota richness and decreased the Firmicutes-to-Bacteroidetes ratio. Changes in serum markers were found to be correlated with the plasma metabolites, including sphingosine, trehalose, and 3-methoxy-4-hydroxyphenylglycol sulfate, and gut microbiota such as Ruminococcaceae_NK4A214, Alistipes, and Bacteroides. Overall, these results suggest that the BG promotes growth and health of pre-weaning dairy calves by affecting the interaction between the host and gut microbiota.

Item Type:Articles
Additional Information:This research was funded by the Sichuan Science and Technology Program (No. 2019YJ0671) and the Key R&D Program Supported by the Department of Science and Technology of Gansu Province (No. 20YF8NA029).
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Huang, Yixin
Creator Roles:
Huang, Y.Formal analysis, Writing – original draft, Writing – review and editing, Visualization
Authors: Luo, Z., Ma, L., Zhou, T., Huang, Y., Zhang, L., Du, Z., Yong, K., Yao, X., Shen, L., Yu, S., Shi, X., and Cao, S.
College/School:College of Medical Veterinary and Life Sciences > School of Biodiversity, One Health & Veterinary Medicine
Journal Name:Metabolites
Publisher:MDPI
ISSN:2218-1989
ISSN (Online):2218-1989
Published Online:26 July 2022
Copyright Holders:Copyright © 2022 The Authors
First Published:First published in Metabolites 12(8): 687
Publisher Policy:Reproduced under a Creative Commons License

University Staff: Request a correction | Enlighten Editors: Update this record