The end of the line for hookworm? An update on vaccine development

Devaney, E. (2005) The end of the line for hookworm? An update on vaccine development. PLoS Medicine, 2(10), e327. (doi: 10.1371/journal.pmed.0020327)

Abstract

Human hookworms are parasitic nematodes infecting about 700 million individuals, largely in tropical regions of the world [1]. In endemic areas, most infected people carry a mixed worm burden, including Ascaris lumbricoides (roundworms), Trichuris trichuria (whipworms), and Ancylostoma duodenale and/or Necator americanus (both hookworms). Of these soil-transmitted helminths, hookworms are the most pathogenic because of their propensity to feed on blood, resulting in anaemia, particularly in those with low iron reserves such as children and women of reproductive age.

• Item Type: Articles
• Additional Information: This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Devaney, Professor Eileen
• Authors: Devaney, E.
• College/School: College of Medical Veterinary and Life Sciences > School of Infection & Immunity
• Journal Name: PLoS Medicine
• Publisher: Public Library of Science
• ISSN: 1549-1277
• ISSN (Online): 1549-1676
• Published Online: 04 October 2005
• Copyright Holders: © 2005 Eileen Devaney
• First Published: First published in PLoS Medicine 2005 2(10): e327
• Publisher Policy: Reproduced in accordance with the copyright policy of the publisher

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