pH sensitive water-in-water emulsions based on the pullulan and poly(N,N-dimethylacrylamide) aqueous two-phase system

Plucinski, A. and Schmidt, B. V. K. J. (2022) pH sensitive water-in-water emulsions based on the pullulan and poly(N,N-dimethylacrylamide) aqueous two-phase system. Polymer Chemistry, 13(18), pp. 4170-4177. (doi: 10.1039/D2PY00469K)

Abstract

Aqueous-two phase systems (ATPS) and water-in-water (w/w) emulsions are a major topic in chemistry and biology, mainly due to their biocompatibility and various applications. In here, the ATPS formed from poly(N,N-dimethylacrylamide) (PDMA) with three different molar masses (24k – 106 g mol−1) and commercial pullulan is investigated. Additionally, the ATPS with ultra-high molecular weight PDMA was transformed into a w/w emulsion using a pH-responsive block copolymer as stabiliser. The w/w emulsion could be destabilised or stabilised, depending on the current pH. The novel pH sensitive w/w emulsion will open up new pathways for example for the encapsulation of biomolecules.

• Item Type: Articles
• Additional Information: The authors acknowledge Marlies Gräwert and June Southall for SEC measurements. B. S. and A. P. acknowledge funding from the University of Glasgow and the German Research Foundation (grant no. SCHM 3282/3-1).
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Plucinski, Alexander and Schmidt, Dr Bernhard
• Authors: Plucinski, A., and Schmidt, B. V. K. J.
• College/School: College of Science and Engineering > School of Chemistry
• Journal Name: Polymer Chemistry
• Publisher: Royal Society of Chemistry
• ISSN: 1759-9954
• ISSN (Online): 1759-9962
• Published Online: 28 June 2022
• Copyright Holders: Copyright © 2022 The Royal Society of Chemistry
• First Published: First published in Polymer Chemistry 13(18): 4170-4177
• Publisher Policy: Reproduced under a Creative Commons licence