Emergency surgical decompression and long term survival of glioblastoma presenting in coma in old age: case report and review of prognostic factors

McKinley, A., Lammy, S. , James, A. , Stan, A. and Barrett, C. (2022) Emergency surgical decompression and long term survival of glioblastoma presenting in coma in old age: case report and review of prognostic factors. Oxford Medical Case Reports, 2022(7), pp. 271-273. (doi: 10.1093/omcr/omac074) (PMID:35903619) (PMCID:PMC9318890)

Abstract

We present a case demonstrating that older age does not exclude long-term survival with glioblastoma. This is a malignant neoplasm with a median life expectancy of 14 months in patients treated with radical intent. Survival is dependent on several independent and interacting prognostic factors of which advancing age is a negative factor. We present a septuagenarian with a 3.5-year survival following aggressive management. The potential to improve glioblastoma survival in an elderly population by examination of additional prognostic factors and identifying biomarkers warrants further research.

• Item Type: Articles
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Barrett, Mr Chris and James, Dr Allan and Lammy, Dr Simon
• Authors: McKinley, A., Lammy, S., James, A., Stan, A., and Barrett, C.
• College/School: College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing
• Journal Name: Oxford Medical Case Reports
• Publisher: Oxford University Press
• ISSN: 2053-8855
• ISSN (Online): 2053-8855
• Published Online: 26 July 2022
• Copyright Holders: Copyright © The Author(s) 2022
• First Published: First published in Oxford Medical Case Reports 2022(7): 271-273
• Publisher Policy: Reproduced under a Creative Commons licence