The prospects of non-EEG seizure detection devices in dogs

Bongers, J., Gutierrez-Quintana, R. and Stalin, C. E. (2022) The prospects of non-EEG seizure detection devices in dogs. Frontiers in Veterinary Science, 9, 896030. (doi: 10.3389/fvets.2022.896030) (PMID:35677934) (PMCID:PMC9168902)

Abstract

The unpredictable nature of seizures is challenging for caregivers of epileptic dogs, which calls the need for other management strategies such as seizure detection devices. Seizure detection devices are systems that rely on non-electroencephalographic (non-EEG) ictal changes, designed to detect seizures. The aim for its use in dogs would be to provide owners with a more complete history of their dog's seizures and to help install prompt (and potentially life-saving) intervention. Although seizure detection via wearable intracranial EEG recordings is associated with a higher sensitivity in humans, there is robust evidence for reliable detection of generalized tonic-clonic seizures (GTCS) using non-EEG devices. Promising non-EEG changes described in epileptic humans, include heart rate variability (HRV), accelerometry (ACM), electrodermal activity (EDA), and electromyography (EMG). Their sensitivity and false detection rate to detect seizures vary, however direct comparison of studies is nearly impossible, as there are many differences in study design and standards for testing. A way to improve sensitivity and decrease false-positive alarms is to combine the different parameters thereby profiting from the strengths of each one. Given the challenges of using EEG in veterinary clinical practice, non-EEG ictal changes could be a promising alternative to monitor seizures more objectively. This review summarizes various seizure detection devices described in the human literature, discusses their potential use and limitations in veterinary medicine and describes what is currently known in the veterinary literature.

• Item Type: Articles
• Keywords: Veterinary Science, wearable, technology, canine, epilepsy, review, seizure detection, dog
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Bongers, Jos and Stalin, Mrs Catherine and Gutierrez Quintana, Mr Rodrigo
• Authors: Bongers, J., Gutierrez-Quintana, R., and Stalin, C. E.
• College/School: College of Medical Veterinary and Life Sciences > School of Biodiversity, One Health & Veterinary Medicine
• Journal Name: Frontiers in Veterinary Science
• Publisher: Frontiers Media
• ISSN: 2297-1769
• ISSN (Online): 2297-1769
• Copyright Holders: Copyright © 2022 Bongers, Gutierrez-Quintana and Stalin
• First Published: First published in Frontiers in Veterinary Science 9: 896030
• Publisher Policy: Reproduced under a Creative Commons licence