Kontorinis, G. and Han, A. Y. (2023) A systematic review on delayed acquisition of post-gadolinium MRI in meniere’s disease: imaging of the endolymphatic spaces. Journal of Laryngology and Otology, 137(3), pp. 239-245. (doi: 10.1017/S0022215122001347) (PMID:35674257)
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Abstract
Objectives: To assess the clinical implications of delayed-acquisition post-gadolinium Magnetic Resonance Imaging (MRI) in identifying endolymphatic hydrops (EH) in Meniere’s disease (MD). Methods: We performed a systematic review including Medline and Embase following the PRISMA guidelines with predetermined criteria, namely MD, post-gadolinium MRI and EH; we used QUADAS-2 to assess bias. Results: Eleven studies were included; they all used 3T MRI with 3D-FLAIR being the most common sequence. Intravenous gadolinium administration was more widely used compared to the intratympanic route. As for the timing of acquisition, 4 hours post-administration was universally used for the IV and 24 hours for the IT gadolinium. Despite patient-selection associated bias, all studies reported adequate visualisation of the endolymphatic spaces. Conclusion: The use of delayed-acquisition MRI is increasingly supported in visualising the endolymphatic spaces in MD. While the accessibility of 3T MRI questions its wider applicability, it is a promising tool for the near future.
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Kontorinis, Mr Georgios |
Authors: | Kontorinis, G., and Han, A. Y. |
College/School: | College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing |
Journal Name: | Journal of Laryngology and Otology |
Publisher: | Cambridge University Press |
ISSN: | 0022-2151 |
ISSN (Online): | 1748-5460 |
Published Online: | 08 June 2022 |
Copyright Holders: | Copyright © 2022 The Authors |
First Published: | First published in Journal of Laryngology and Otology 137(3): 239-245 |
Publisher Policy: | Reproduced in accordance with the publisher copyright policy |
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