McGuffin, L. J., Street, S. A., Bryson, K. , Sørensen, S.‐A. and Jones, D. T. (2004) The Genomic Threading Database: A comprehensive resource for structural annotations of the genomes from key organisms. Nucleic Acids Research, 32(suppl1), D196-D199. (doi: 10.1093/nar/gkh043) (PMID:14681393) (PMCID:PMC308777)
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Abstract
Currently, the Genomic Threading Database (GTD) contains structural assignments for the proteins encoded within the genomes of nine eukaryotes and 101 prokaryotes. Structural annotations are carried out using a modified version of GenTHREADER, a reliable fold recognition method. The Gen THREADER annotation jobs are distributed across multiple clusters of processors using grid technology and the predictions are deposited in a relational database accessible via a web interface at http://bioinf.cs.ucl.ac.uk/GTD . Using this system, up to 84% of proteins encoded within a genome can be confidently assigned to known folds with 72% of the residues aligned. On average in the GTD, 64% of proteins encoded within a genome are confidently assigned to known folds and 58% of the residues are aligned to structures.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Bryson, Dr Kevin |
| Authors: | McGuffin, L. J., Street, S. A., Bryson, K., Sørensen, S.‐A., and Jones, D. T. |
| College/School: | College of Science and Engineering > School of Computing Science |
| Journal Name: | Nucleic Acids Research |
| Publisher: | Oxford University Press |
| ISSN: | 0305-1048 |
| ISSN (Online): | 1362-4962 |
| Related URLs: |
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