The cell biology of receptor-mediated virus entry

Grove, J. and Marsh, M. (2011) The cell biology of receptor-mediated virus entry. Journal of Cell Biology, 195(7), pp. 1071-1082. (doi: 10.1083/jcb.201108131) (PMID:22123832) (PMCID:PMC3246895)

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The cell imposes multiple barriers to virus entry. However, viruses exploit fundamental cellular processes to gain entry to cells and deliver their genetic cargo. Virus entry pathways are largely defined by the interactions between virus particles and their receptors at the cell surface. These interactions determine the mechanisms of virus attachment, uptake, intracellular trafficking, and, ultimately, penetration to the cytosol. Elucidating the complex interplay between viruses and their receptors is necessary for a full understanding of how these remarkable agents invade their cellular hosts.

Item Type:Articles
Glasgow Author(s) Enlighten ID:Grove, Dr Joe
Authors: Grove, J., and Marsh, M.
College/School:College of Medical Veterinary and Life Sciences > School of Infection & Immunity > Centre for Virus Research
Journal Name:Journal of Cell Biology
Publisher:Rockefeller University Press
ISSN (Online):1540-8140
Published Online:28 November 2011
Copyright Holders:Copyright © 2011 Grove and Marsh
First Published:First published in Journal of Cell Biology 195(7): 1071-1082
Publisher Policy:Reproduced under a Creative Commons License

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