Super-resolution microscopy: a virus' eye view of the cell

Grove, J. (2014) Super-resolution microscopy: a virus' eye view of the cell. Viruses, 6(3), pp. 1365-1378. (doi: 10.3390/v6031365) (PMID:24651030) (PMCID:PMC3970155)

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It is difficult to observe the molecular choreography between viruses and host cell components, as they exist on a spatial scale beyond the reach of conventional microscopy. However, novel super-resolution microscopy techniques have cast aside technical limitations to reveal a nanoscale view of virus replication and cell biology. This article provides an introduction to super-resolution imaging; in particular, localisation microscopy, and explores the application of such technologies to the study of viruses and tetraspanins, the topic of this special issue.

Item Type:Articles
Glasgow Author(s) Enlighten ID:Grove, Dr Joe
Authors: Grove, J.
College/School:College of Medical Veterinary and Life Sciences > School of Infection & Immunity > Centre for Virus Research
Journal Name:Viruses
ISSN (Online):1999-4915
Published Online:19 March 2014
Copyright Holders:Copyright © 2014 The Authors
First Published:First published in Viruses 6(3): 1365-1378
Publisher Policy:Reproduced under a Creative Commons License

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