Investigating hepatitis C virus infection using super-resolution microscopy

pereira, P. M., Jacobs, C. and Grove, J. (2018) Investigating hepatitis C virus infection using super-resolution microscopy. In: Law, M. (ed.) Hepatitis C Virus Protocols. Series: Methods in molecular biology (1911). Humana Press: New York, NY, pp. 247-261. ISBN 9781493989751 (doi: 10.1007/978-1-4939-8976-8_17)

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Super-resolution microscopy (SRM) can provide a window on the nanoscale events of virus replication. Here we describe a protocol for imaging hepatitis C virus-infected cells using localization SRM. We provide details on sample preparation, immunostaining, data collection, and super-resolution image reconstruction. We have made all efforts to generalize the protocol to make it accessible to all budding super-resolution microscopists.

Item Type:Book Sections
Glasgow Author(s) Enlighten ID:Grove, Dr Joe
Authors: pereira, P. M., Jacobs, C., and Grove, J.
College/School:College of Medical Veterinary and Life Sciences > School of Infection & Immunity > Centre for Virus Research
Publisher:Humana Press
Published Online:29 December 2018

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