Qi, N., Lockington, D., Wang, L., Ramaesh, K. and Luo, X. (2022) Estimations of critical clear corneal incisions required for lens insertion in cataract surgery: a mathematical aspect. Frontiers in Physiology, 13, 834214. (doi: 10.3389/fphys.2022.834214) (PMID:35464073) (PMCID:PMC9023857)
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Abstract
In a routine cataract operation cornea tissue may be damaged when an intra-ocular lens (IOL) injector of diameter between 1.467mm-2.011mm is inserted through an empirically designed 2.2mm corneal incision. We aimed to model and estimate the minimal length of the incision required to avoid wound tear. It was assumed that the damage was caused by tissue fracture at the tips of the incision, and this fracture could be studied using damage and fracture mechanics. The criterion of the damage was caused by a tear governed by the critical energy release rate (ERR) Gc, which is tissue dependent. Analytical and numerical studies were both conducted indicating the possibility of a safe and effective incision in cataract surgery. Six commonly used IOL injection systems were examined. Our results suggested that the recommended 2.2mm incision cannot be treated as a universal threshold. Quicker IOL insertion may reduce wound damage. It was also recommended to advance IOL injector via its minor axis, and to cut the tear preferably along the circumferential direction due to tissue orthotropy. This study provides useful information and a deeper insight into the potential for mechanical damage to the corneal wound in cataract surgery.
Item Type: | Articles |
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Additional Information: | We gratefully acknowledge the financial support from the National Natural Science Foundation of China (No. 11902181), the National Natural Science Foundation of Shandong Province (No. ZR2019QA014), and the United Kingdom EPSRC grants (EP/S030875/1 and EP/S020950/1). |
Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Luo, Professor Xiaoyu and Qi, Dr Nan and Ramaesh, Dr Kanna |
Creator Roles: | Qi, N.Conceptualization, Methodology, Investigation, Visualization, Formal analysis, Writing – original draft Ramaesh, K.Investigation, Writing – review and editing Luo, X.Conceptualization, Methodology, Writing – review and editing |
Authors: | Qi, N., Lockington, D., Wang, L., Ramaesh, K., and Luo, X. |
College/School: | College of Medical Veterinary and Life Sciences College of Science and Engineering > School of Mathematics and Statistics > Mathematics |
Journal Name: | Frontiers in Physiology |
Publisher: | Frontiers Media |
ISSN: | 1664-042X |
ISSN (Online): | 1664-042X |
Copyright Holders: | Copyright © 2022 The Authors |
First Published: | First published in Frontiers in Physiology 13:834214 |
Publisher Policy: | Reproduced under a Creative Commons License |
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