Use of Bordetella bronchiseptica and Bordetella pertussis as live vaccines and vectors for heterologous antigens

Stevenson, A. and Roberts, M. (2003) Use of Bordetella bronchiseptica and Bordetella pertussis as live vaccines and vectors for heterologous antigens. FEMS Immunology and Medical Microbiology, 37, pp. 121-128. (doi: 10.1016/S0928-8244(03)00068-3)

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Abstract

<i>Bordetella bronchiseptica</i> and <i>Bordetella pertussis</i>are respiratory pathogens of humans and animals respectively. Unlike many bacteria, they are able to efficiently colonise healthy ciliated respiratory mucosa. This characteristic of <i>Bordetella spp.</i> can potentially be exploited to develop efficient live vaccines and vectors for delivery of heterologous antigens to the respiratory tract. Here we review the progress in this area.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Roberts, Professor Mark
Authors: Stevenson, A., and Roberts, M.
College/School:College of Medical Veterinary and Life Sciences > School of Biodiversity, One Health & Veterinary Medicine
Journal Name:FEMS Immunology and Medical Microbiology
Publisher:Wiley
ISSN:0928-8244
ISSN (Online):1574-695X
Published Online:09 January 2006

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