Fentem, R., de Stefani, A., Gutierrez Quintana, R. , Alcoverro, E., Jones, G. M. C., Amengual-Batle, P. and Gonçalves, R. (2022) Risk factors associated with short‐term mortality and recurrence of status epilepticus in dogs. Journal of Veterinary Internal Medicine, 36(2), pp. 656-662. (doi: 10.1111/jvim.16353) (PMID:34994484) (PMCID:PMC8965210)
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Abstract
Background: Status epilepticus (SE) is an emergency associated with serious consequences for both patient and owner. Data regarding risk factors for short-term mortality or recurrence in dogs with SE is limited. Objective: Identify risk factors associated with short-term mortality (euthanasia or spontaneous death) and recurrence of SE in dogs. Animals: One hundred twenty-four client-owned dogs that sustained an episode of SE. Methods: Retrospective multicenter study using data collected from medical records of dogs presented in SE to the contributing institutions. Multivariable logistic regression analysis was performed using a manual backwards stepwise approach to identify risk factors associated with short-term mortality and recurrence of SE after discharge. Results: Short-term mortality for affected dogs was 29.8%. Factors significantly associated with short-term mortality included increased patient age, shorter duration of hospitalization, development of SE before arrival, and SE caused by a potentially fatal etiology. Status epilepticus recurred in 27% of dogs that survived to discharge. Factors significantly associated with recurrence of SE included prior history of pharmacoresistant epilepsy and predominance of a focal seizure phenotype. Conclusions and Clinical Importance: Our results may be used to inform clinicians and dog owners regarding risk factors for both short-term mortality and recurrence in dogs with SE.
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Amengual Batle, Pablo and Gutierrez Quintana, Mr Rodrigo |
Authors: | Fentem, R., de Stefani, A., Gutierrez Quintana, R., Alcoverro, E., Jones, G. M. C., Amengual-Batle, P., and Gonçalves, R. |
College/School: | College of Medical Veterinary and Life Sciences > School of Biodiversity, One Health & Veterinary Medicine |
Journal Name: | Journal of Veterinary Internal Medicine |
Publisher: | Wiley |
ISSN: | 0891-6640 |
ISSN (Online): | 1939-1676 |
Published Online: | 07 January 2022 |
Copyright Holders: | Copyright © 2022 The Authors |
First Published: | First published in Journal of Veterinary Internal Medicine 36(2): 656-662 |
Publisher Policy: | Reproduced under a Creative Commons Licence |
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