Economic evaluation of population-based type 2 diabetes mellitus screening at different healthcare settings in Vietnam

Toi, P. L., Wu, O. , Thavorncharoensap, M., Srinonprasert, V., Anothaisintawee, T., Thakkinstian, A., Phuong, N. K. and Chaikledkaew, U. (2021) Economic evaluation of population-based type 2 diabetes mellitus screening at different healthcare settings in Vietnam. PLoS ONE, 16(12), e0261231. (doi: 10.1371/journal.pone.0261231) (PMID:34941883) (PMCID:PMC8700026)

Abstract

Introduction: Few economic evaluations have assessed the cost-effectiveness of screening type-2 diabetes mellitus (T2DM) in different healthcare settings. This study aims to evaluate the value for money of various T2DM screening strategies in Vietnam. Methods: A decision analytical model was constructed to compare costs and quality-adjusted life years (QALYs) of T2DM screening in different health care settings, including (1) screening at commune health station (CHS) and (2) screening at district health center (DHC), with no screening as the current practice. We further explored the costs and QALYs of different initial screening ages and different screening intervals. Cost and utility data were obtained by primary data collection in Vietnam. Incremental cost-effectiveness ratios were calculated from societal and payer perspectives, while uncertainty analysis was performed to explore parameter uncertainties. Results: Annual T2DM screening at either CHS or DHC was cost-effective in Vietnam, from both societal and payer perspectives. Annual screening at CHS was found as the best screening strategy in terms of value for money. From a societal perspective, annual screening at CHS from initial age of 40 years was associated with 0.40 QALYs gained while saving US$ 186.21. Meanwhile, one-off screening was not cost-effective when screening for people younger than 35 years old at both CHS and DHC. Conclusions: T2DM screening should be included in the Vietnamese health benefits package, and annual screening at either CHS or DHC is recommended.

• Item Type: Articles
• Additional Information: Funding: This study was supported by Mahidol University and the International Decision Support Initiative (iDSI) through a grant awarded to UC (OPP1087363)
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Wu, Professor Olivia
• Authors: Toi, P. L., Wu, O., Thavorncharoensap, M., Srinonprasert, V., Anothaisintawee, T., Thakkinstian, A., Phuong, N. K., and Chaikledkaew, U.
• College/School: College of Medical Veterinary and Life Sciences > School of Health & Wellbeing > Health Economics and Health Technology Assessment
• Journal Name: PLoS ONE
• Publisher: Public Library of Science
• ISSN: 1932-6203
• ISSN (Online): 1932-6203
• Published Online: 23 December 2021
• Copyright Holders: Copyright: © 2021 Toi et al
• First Published: First published in PLoS ONE 16(12): e0261231
• Publisher Policy: Reproduced under a Creative Commons licence