What matters to patients and clinicians when discussing the impact of cancer medicines on health-related quality of life? Consensus-based mixed methods approach in prostate cancer

Dunlop, E. et al. (2022) What matters to patients and clinicians when discussing the impact of cancer medicines on health-related quality of life? Consensus-based mixed methods approach in prostate cancer. Supportive Care in Cancer, 30(4), pp. 3141-3150. (doi: 10.1007/s00520-021-06724-6) (PMID:34878587) (PMCID:PMC8857102)

Abstract

Objective: To identify what matters to clinicians and patients when discussing cancer medicines’ impact on health-related quality of life (HRQoL). Methods: A framework of HRQoL domain/domain elements was developed, informed by analysis of published patient reported outcome measures (PROMs), applicable to prostate cancer. Using mixed methods (eDelphi, Nominal Group Technique and questionnaire), prostate cancer clinicians and patients attending prostate cancer clinics and support groups were asked which domains/domain elements would be important to them when discussing the impact prostate cancer medicines have on their HRQoL. Results: Twenty-one clinicians and 71 patients participated from the West of Scotland. Clinicians and patients identified 53/62 domain elements across seven domains as important, of which 32 (60%) were common to both groups. Clinicians placed more importance than patients on Mood & Emotion; in contrast, patients placed importance on a broader range of Symptoms & Side Effects, being informed about their care, and having effective healthcare professional collaboration. Conclusion: This study provides insight into the similarities and differences between what clinicians and patients think is important when discussing the impact of cancer medicines on HRQoL. Future research should involve exploring the potential for consistency of medicines PROMs across different cancer types to support patient-clinician communication and drive improvements in care.

• Item Type: Articles
• Additional Information: The Cancer Medicines Outcomes Programme (CMOP) is funded by the Scottish Government.
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Jones, Professor Robert and Glen, Dr Hilary and Wu, Professor Olivia
• Authors: Dunlop, E., Ferguson, A., Mueller, T., Baillie, K., Clarke, J., Laskey, J., Kurdi, A., Wu, O., Jones, R., Glen, H., and Bennie, M.
• College/School: College of Medical Veterinary and Life Sciences > School of Cancer Sciences; College of Medical Veterinary and Life Sciences > School of Health & Wellbeing > Health Economics and Health Technology Assessment
• Journal Name: Supportive Care in Cancer
• Publisher: Springer
• ISSN: 0941-4355
• ISSN (Online): 1433-7339
• Published Online: 08 December 2021
• Copyright Holders: Copyright © 2021 The Authors
• First Published: First published in Supportive Care in Cancer 30(4): 3141-3150
• Publisher Policy: Reproduced under a Creative Commons License