An unusual cause of paraesthesia in a neo-adjuvant gastro-oesophageal cancer

Derby, S. , Graham, J. and McIntosh, D. (2019) An unusual cause of paraesthesia in a neo-adjuvant gastro-oesophageal cancer. BMJ Case Reports, 12(8), e225450. (doi: 10.1136/bcr-2018-225450) (PMID:31444258) (PMCID:PMC6721004)

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Abstract

There is ongoing debate about the best neo-adjuvant strategy for localised resectable oesophageal cancer, however chemotherapy is often employed. Both oesophageal cancer and cisplatin carry an increased risk of thrombosis. Here, we look at an unusual finding in a previously fit woman who presented following neo-adjuvant chemotherapy for resectable oesophageal cancer with increasing difficulty in walking and lower limb paraesthesia. This case looks particularly at the diagnostic challenge and concerns raised in a patient undergoing radical treatment as well as the challenge of complications secondary to treatment with chemotherapy. Willingness to reassess and revisit is a vital part of the diagnostic process. Vascular complications of a disease can be notorious to diagnose and, as in this case can mimic arguably more logical diagnoses. Cancer care provides the unique challenge of investigating unusual presentations related both to disease and treatment.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Graham, Dr Janet and Derby, Dr Sarah
Authors: Derby, S., Graham, J., and McIntosh, D.
Subjects:R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer)
College/School:College of Medical Veterinary and Life Sciences > School of Cancer Sciences
Journal Name:BMJ Case Reports
Publisher:BMJ Publishing Group
ISSN:1757-790X
ISSN (Online):1757-790X
Published Online:22 August 2019

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