Polychlorinated biphenyls are associated with reduced testes weights in harbour porpoises (Phocoena phocoena)

Williams, R. S. et al. (2021) Polychlorinated biphenyls are associated with reduced testes weights in harbour porpoises (Phocoena phocoena). Environment International, 150, 106303. (doi: 10.1016/j.envint.2020.106303) (PMID:33454091)

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Polychlorinated biphenyls (PCBs) are highly toxic and persistent aquatic pollutants that are known to bioaccumulate in a variety of marine mammals. They have been associated with reduced recruitment rates and population declines in multiple species. Evidence to date documents effects of PCB exposures on female reproduction, but few studies have investigated whether PCB exposure impacts male fertility. Using blubber tissue samples of 99 adult and 168 juvenile UK-stranded harbour porpoises (Phocoena phocoena) collected between 1991 and 2017, here we show that PCBs exposures are associated with reduced testes weights in adults with good body condition. In animals with poor body condition, however, the impact of PCBs on testes weights was reduced, conceivably due to testes weights being limited by nutritional stress. This is the first study to investigate the relationship between PCB contaminant burden and testes weights in cetaceans and represents a substantial advance in our understanding of the relationship between PCB exposures and male reproductive biology in cetaceans. As testes weight is a strong indicator of male fertility in seasonally breeding mammals, we suggest the inclusion of such effects in population level impact assessments involving PCB exposures. Given the re-emergent PCB threat our findings are globally significant, with potentially serious implications for long-lived mammals. We show that more effective PCB controls could have a substantial impact on the reproductive health of coastal cetacean species and that management actions may need to be escalated to ensure adequate protection of the most vulnerable cetacean populations.

Item Type:Articles
Additional Information:The first author was funded by the Natural Environment Research Council (NERC) grant NE/L002485/1. D.J.C. is funded by the Bertarelli Foundation through the Bertarelli Programme in Marine Science. P.D.J was partially funded by NERC grant NE/S000100/1 supporting the ChemPop project.
Glasgow Author(s) Enlighten ID:ten Doeschate, Mariel and Davison, Mr Nick and Brownlow, Dr Andrew
Creator Roles:
Brownlow, A.Data curation, Writing – review and editing
ten Doeschate, M.Data curation, Writing – review and editing
Authors: Williams, R. S., Curnick, D. J., Brownlow, A., Barber, J. L., Barnett, J., Davison, N. J., Deaville, R., ten Doeschate, M., Perkins, M., Jepson, P. D., and Jobling, S.
College/School:College of Medical Veterinary and Life Sciences
College of Medical Veterinary and Life Sciences > School of Biodiversity, One Health & Veterinary Medicine
Journal Name:Environment International
ISSN (Online):1873-6750
Published Online:13 January 2021
Copyright Holders:Copyright © 2020 The Authors
First Published:First published in Environment International 150: 106303
Publisher Policy:Reproduced under a Creative Commons License

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