Guía basada en la evidencia. Diagnóstico y manejo del síndrome de Guillain-Barré en diez pasos = Evidence based guidelines. Diagnosis and management of Guillain-Barré syndrome in ten steps

Leonhard, S. E. et al. (2021) Guía basada en la evidencia. Diagnóstico y manejo del síndrome de Guillain-Barré en diez pasos = Evidence based guidelines. Diagnosis and management of Guillain-Barré syndrome in ten steps. Medicina, 81(5), pp. 817-836. (PMID:34633957)

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Abstract

Guillain-Barré syndrome (GBS) is a rare, but potentially fatal, immune-mediated disease of the peripheral nerves and nerve roots that is usually triggered by infections. The incidence of GBS can therefore increase during outbreaks of infectious diseases, as was seen during the Zika virus epidemics in 2013 in French Polynesia and in 2015 in Latin America. Diagnosis and management of GBS can be complicated as its clinical presentation and disease course are heterogeneous, and no international clinical guidelines are currently available. To support clinicians, especially in the context of an outbreak, we have developed a globally applicable guideline for the diagnosis and management of GBS. The guideline is based on current literature and expert consensus, and has a ten-step structure to facilitate its use in clinical practice. We first provide an introduction to the diagnostic criteria, clinical variants and differential diagnoses of GBS. The ten steps then cover early recognition and diagnosis of GBS, admission to the intensive care unit, treatment indication and selection, monitoring and treatment of disease progression, prediction of clinical course and outcome, and management of complications and sequelae.

Item Type:Articles
Keywords:Disease outbreaks, diagnosis, Guillain-Barre Syndrome - diagnosis - epidemiology - therapy, Zika virus Infection - diagnosis - epidemiology - therapy, Zika virus, Guillain-Barré syndrome, management, Incidence, Zika virus, guideline, ascending paralysis, humans.
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Willison, Professor Hugh
Authors: Leonhard, S. E., Mandarakas, M. R., de Assis Aquino Gondim, F., Bateman, K., Brito Ferreira, M. L., Cornblath, D. R., Van Doorn, P. A., Dourado, M. E., Hughes, R. A.C., Islam, B., Kusunoki, S., Pardo, C. A., Reisin, R., Sejvar, J. J., Shahrizaila, N., Soares, C., Umapathi, T., Wang, Y., Yiu, E. M., Willison, H. J., and Jacobs, B. C.
College/School:College of Medical Veterinary and Life Sciences > School of Infection & Immunity
Research Centre:College of Medical Veterinary and Life Sciences > School of Infection & Immunity > Centre for Immunobiology
Journal Name:Medicina
Publisher:Fundación Revista Medicina
ISSN:0025-7680
ISSN (Online):1669-9106
Copyright Holders:Copyright © 2021 The Authors
First Published:First published in Medicina 81(5): 817-836
Publisher Policy:Reproduced under a Creative Commons License

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