Effect of ventricle motion on the dynamic behaviour of chorded mitral valves

Watton, P.N. , Luo, X.Y. , Yin, M., Bernacca, G.M. and Wheatley, D.J. (2008) Effect of ventricle motion on the dynamic behaviour of chorded mitral valves. Journal of Fluids and Structures, 24(1), pp. 58-74. (doi: 10.1016/j.jfluidstructs.2007.06.004)

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An Immersed Boundary (IB) model is employed to investigate the dynamic behaviour of a novel chorded mitral prosthesis, which is in the early stages of its development, under physiological flow conditions. In vivo magnetic resonance images (MRIs) of the left ventricle are analysed to determine the relative motion of the mitral annulus and the papillary muscle regions of the ventricle. The dynamic boundary conditions are incorporated into IB simulations to test the valve in a more realistic dynamic geometric environment. The IB model has successfully identified the effect of the dynamic boundary conditions on the mechanical behaviour of the valve and revealed the strengths and weaknesses of the current mitral design. The mechanical performance of the prosthesis is compared with recent studies of native porcine valves; differences in mechanical behaviour are observed. Potential improvements for the design of the prosthesis are proposed.

Item Type:Articles
Keywords:Immersed Boundary, Mitral valve, Prosthetic heart valve, Static and dynamic loading, Ventricle motion, Papillary muscle, Fluid–structure interactions
Glasgow Author(s) Enlighten ID:Luo, Professor Xiaoyu and Watton, Dr Paul
Authors: Watton, P.N., Luo, X.Y., Yin, M., Bernacca, G.M., and Wheatley, D.J.
Subjects:R Medicine > RC Internal medicine
Q Science > QC Physics
College/School:College of Science and Engineering > School of Mathematics and Statistics > Mathematics
Journal Name:Journal of Fluids and Structures
Journal Abbr.:J. Fluid Struct.
ISSN (Online):1095-8622
Published Online:20 September 2007

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