Maan, S., Maan, N. S., Guimera, M., Nomikou, K. , Singh, K. P., Pullinger, G., Belaganahalli, M. N. and Mertens, P. P.C. (2012) Genome sequence of a reassortant strain of bluetongue virus serotype 23 from western India. Journal of Virology, 86(12), pp. 7011-7012. (doi: 10.1128/JVI.00731-12) (PMID:22628397) (PMCID:PMC3393570)
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Abstract
The full genome sequence (19,177 bp) of an Indian strain (IND1988/02) of bluetongue virus (BTV) serotype 23 was determined. This virus was isolated from a sheep that had been killed during a severe bluetongue outbreak that occurred in Rahuri, Maharashtra State, western India, in 1988. Phylogenetic analyses of these data demonstrate that most of the genome segments from IND1988/02 belong to the major “eastern” BTV topotype. However, genome segment 5 belongs to the major “western” BTV topotype, demonstrating that IND1988/02 is a reassortant. This may help to explain the increased virulence that was seen during this outbreak in 1988. Genome segment 5 of IND1988/02 shows >99% sequence identity with some other BTV isolates from India (e.g., BTV-3 IND2003/08), providing further evidence of the existence and circulation of reassortant strains on the subcontinent.
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Mertens, Professor Peter and Pullinger, Dr Gillian and Nomikou, Dr Kyriaki and Guimera Busquets, Marc |
Authors: | Maan, S., Maan, N. S., Guimera, M., Nomikou, K., Singh, K. P., Pullinger, G., Belaganahalli, M. N., and Mertens, P. P.C. |
College/School: | College of Medical Veterinary and Life Sciences > School of Infection & Immunity > Centre for Virus Research College of Medical Veterinary and Life Sciences > School of Biodiversity, One Health & Veterinary Medicine |
Journal Name: | Journal of Virology |
Publisher: | American Society for Microbiology |
ISSN: | 0022-538X |
ISSN (Online): | 1098-5514 |
Published Online: | 24 May 2012 |
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