Page, R. D. M. and Cotton, J. A. (2000) Genetree: a tool for exploring gene family evolution. In: Sankoff, D. and Nadeau, J. H. (eds.) Comparative Genomics: Empirical and Analytical Approaches to Gene Order Dynamics, Map Alignment and the Evolution of Gene Families. Series: Computational Biology. Springer: Dodrecht, pp. 525-536. ISBN 9780792365846 (doi: 10.1007/978-94-011-4309-7_45)
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Abstract
Molecular biologists interested in the evolution of gene families and molecular systematists interested in the evolution of whole organisms are both concerned with the relationship between gene phylogenies and organism phy-logenies. We present reconciled trees as a tool for exploring this relationship. In discussing recent developments, we focus on techniques which enable researchers to take account of uncertainty in the underlying gene phylogenies and to locate gene duplications and episodes of gene duplication on the species tree. Implementation of these methods should allow rapid, automated analysis of large sets of gene families and even of whole genomes, producing well supported organism phylogenies and allowing us to quantitatively investigate patterns of gene family evolution.
| Item Type: | Book Sections |
|---|---|
| Status: | Published |
| Glasgow Author(s) Enlighten ID: | Page, Professor Roderic |
| Authors: | Page, R. D. M., and Cotton, J. A. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Biodiversity, One Health & Veterinary Medicine |
| Publisher: | Springer |
| ISBN: | 9780792365846 |
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