Toward clinical applications of smartphone spectroscopy and imaging

Peveler, W. J. and Algar, W. R. (2021) Toward clinical applications of smartphone spectroscopy and imaging. In: Crocombe, R., Leary, P. and Kammrath, B. (eds.) Portable Spectroscopy and Spectrometry. Volume 2: Applications. John Wiley and Sons: Hoboken, NJ ; West Sussex, UK, pp. 199-226. ISBN 9781119636403 (doi: 10.1002/9781119636489.ch32)

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This chapter focuses on optical smartphone platforms that are under development and have potential to impact clinical medicine. It aims to revisit how a smartphone camera can be used for optical measurements, including spectroscopy, and how the use of peripherals enables the creation of spectroscopic devices that can measure clinical samples. Smartphone-based imaging systems and spectrometers utilize the camera chip of the smartphone as an optical detector for measurements of light intensity and color. The chapter discusses types of clinical samples, the biomarker content to be analyzed by smartphone spectroscopy and imaging. The distinct advantage to creating a smartphone imaging or spectrometric analysis platform is portability and reduction in instrumentation cost. Smartphone microscopy has been developed, with many commercial devices now available for bright-field imaging. Smartphone cameras can be readily manipulated to read and even perform complete clinical assays for a wide variety of biomarkers in multiple different formats, in both resource-limited and near-patient settings.

Item Type:Book Sections
Glasgow Author(s) Enlighten ID:Peveler, Dr William
Authors: Peveler, W. J., and Algar, W. R.
College/School:College of Science and Engineering > School of Chemistry
Publisher:John Wiley and Sons
Published Online:27 April 2021

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