Profiling early head and neck cancer

Hunter, K., Parkinson, E. and Harrison, P.R. (2005) Profiling early head and neck cancer. Nature Reviews Cancer, 5(2), 127 -135. (doi: 10.1038/nrc1549)

Abstract

Head and neck squamous-cell carcinoma (HNSCC) is the sixth most common cancer worldwide and, disappointingly, survival rates are not improving. Moreover, HNSCC has a severe impact on the quality of life of patients and survivors, and the significant morbidity subsequent to treatment often mandates long-term multidisciplinary care, which places significant financial pressures on the treating institution. Therefore, prevention and early diagnosis of high-risk pre-malignant lesions are high priorities for reducing deaths due to head and neck cancer. Recent advances have begun to elucidate the different aetiologies of HNSCCs in relation to previous pre-malignancies and to identify which pre-malignant lesions are likely to progress to malignancy.

• Item Type: Articles
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Parkinson, Prof Eric and Hunter, Dr Keith and Harrison, Dr Paul
• Authors: Hunter, K., Parkinson, E., and Harrison, P.R.
• Subjects: R Medicine > RK Dentistry
• College/School: College of Medical Veterinary and Life Sciences; College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing; College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing > Dental School
• Journal Name: Nature Reviews Cancer
• ISSN: 1474-175X