Sykes, R. , Doherty, D., Mangion, K., Morrow, A. and Berry, C. (2021) What an interventionalist needs to know about MI with non-obstructive coronary arteries. Interventional Cardiology Review, 16, e10. (doi: 10.15420/icr.2021.10) (PMID:34188694) (PMCID:PMC8218171)
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Publisher's URL: https://doi.org/10.15420/icr.2021.10
Abstract
MI with non-obstructive coronary arteries (MINOCA) is caused by a heterogeneous group of vascular or myocardial disorders. MINOCA occurs in 5–15% of patients presenting with acute ST-segment elevation MI or non-ST segment elevation MI and prognosis is impaired. The diagnosis of MINOCA is made during coronary angiography following acute MI, where there is no stenosis ≥50% present in an infarct-related epicardial artery and no overt systemic aetiology for the presentation. Accurate diagnosis and subsequent management require the appropriate utilisation of intravascular imaging, coronary function testing and subsequent imaging to assess for myocardial disorders without coronary involvement. Although plaque-related MINOCA is currently managed with empirical secondary prevention strategies, there remains an unmet therapeutic need for targeted and evidence-based therapy for MINOCA patients and increased awareness of the recommended diagnostic pathway.
| Item Type: | Articles |
|---|---|
| Additional Information: | CB is supported by research funding from the British Heart Foundation (PG/17/2532884, RE/13/5/30177, RE/18/6/34217). All other authors have no conflicts of interest to declare. |
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Mangion, Dr Kenneth and Morrow, Dr Andrew and Sykes, Dr Robert and Doherty, Dr Daniel and Berry, Professor Colin |
| Authors: | Sykes, R., Doherty, D., Mangion, K., Morrow, A., and Berry, C. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Cardiovascular & Metabolic Health College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing |
| Journal Name: | Interventional Cardiology Review |
| Publisher: | Radcliffe Cardiology |
| ISSN: | 1756-1477 |
| ISSN (Online): | 1756-1485 |
| Published Online: | 10 June 2021 |
| Copyright Holders: | Copyright © 2021 Radcliffe Cardiology |
| First Published: | First published in Interventional Cardiology Review 16:e10 |
| Publisher Policy: | Reproduced under a Creative Commons licence |
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