Gillgrass, T.J., Creanor, S.L., Foye, R.H. and Millett, D.T. (2001) Varnish or polymeric coating for the prevention of demineralization? An ex vivo study. Journal of Orthodontics, 28(4), 291 -295.
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Publisher's URL: http://jorthod.maneyjournals.org/cgi/content/abstract/28/4/291
Abstract
Objective: The ability of an experimental coating, Odyssey, to prevent demineralisation ex vivo was compared with that of a fluoride varnish, Duraphat® and a chlorhexidine-containing varnish, Cervitec. Design: an ex vivo single-blind study. Setting: Hard tissue research laboratory. Materials and methods: thirty bovine enamel blocks 0•5 cm x 1•5 cm were divided into 6 groups of 5 specimens. The enamel blocks were then allocated to one of 6 surface treatments. Interventions: (1) surface left unprepared (control), (2) Duraphat® application, (3) Cervitec application, (4) experimental polymer coating, (5) enamel conditioned with 10% citric acid and coated with the experimental polymer coating Odyssey (O + C), (6) enamel etched for 30 sec with 37% phosphoric acid and coated with the experimental coating (O + E). All specimens were cycled for 7 days through a daily procedure of demineralisation for 4 hours and remineralisation for 20 hours, and exposed to an equivalent of 2 months toothbrushing. A single operator blinded to the treatment allocation of each specimen carried artificial lesion depth assessment out using computer-assisted transverse microradiography. Results: The control group had the greatest mean lesion depth (97•16 + 29•8 µm) with the Duraphat® group exhibiting the lowest mean lesion depth (24•53 + 15•44 µm). The Duraphat®, Odyssey, O + C and O + E groups all had significantly less lesion depth when compared with no surface preparation (p < 0•05 for all comparisons). There were no significant differences between any of the Odyssey groups. Conclusions: The efficacy of Duraphat® application in preventing demineralisation ex vivo has been demonstrated in the present study, but clinical trials are required to assess its usefulness in orthodontic practice.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Gillgrass, Dr Toby and Creanor, Dr Stephen |
| Authors: | Gillgrass, T.J., Creanor, S.L., Foye, R.H., and Millett, D.T. |
| Subjects: | R Medicine > RK Dentistry |
| College/School: | College of Medical Veterinary and Life Sciences College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing > Dental School |
| Journal Name: | Journal of Orthodontics |
| ISSN: | 1465-3125 |
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