A new role for E2F-1 in checkpoint control

La Thangue, N. and Stevens, C. (2003) A new role for E2F-1 in checkpoint control. Cell Cycle, 2(5), pp. 435-437.

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Abstract

In response to DNA damage, E2F-1 is induced and phosphorylated. Phosphorylated E2F-1 can reside in discrete nuclear structures and induce apoptosis, suggesting a unique role for E2F-1 in DNA repair and checkpoint functions.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:UNSPECIFIED
Authors: La Thangue, N., and Stevens, C.
College/School:College of Medical Veterinary and Life Sciences
Journal Name:Cell Cycle

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