P53 and prognosis: New insights and further complexity

Vousden, K. (2005) P53 and prognosis: New insights and further complexity. Cell, 120(1), pp. 7-10. (doi: 10.1016/j.cell.2004.12.027)

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Abstract

Despite the massive amount of knowledge that has accumulated about p53, there is still much to learn about its role in tumor suppression. New papers now provide evidence that levels of Mdm2 in humans or presence of mutant forms of p53 in mice can have profound impacts on survival and tumorigenesis. These findings may lead to new diagnostic and therapeutic approaches to treating cancer patients.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Vousden, Karen
Authors: Vousden, K.
College/School:College of Medical Veterinary and Life Sciences > School of Cancer Sciences
Journal Name:Cell
ISSN:0092-8674

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