Richards, S., Morrison, L. J., Torr, S. J., Barrett, M. P. , Manangwa, O., Mramba, F. and Auty, H. (2021) Pharma to farmer: field challenges of optimizing trypanocide use in African animal trypanosomiasis. Trends in Parasitology, 37(9), pp. 831-843. (doi: 10.1016/j.pt.2021.04.007) (PMID:33962879)
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Abstract
Trypanocides are a key control component of African animal trypanosomiasis (AAT) in tsetse-infested areas of sub-Saharan Africa. While farmers are dependent upon trypanocides, recent research highlights their inappropriate and ineffective use, problems with drug quality, and treatment failure. There are currently gaps in knowledge and investment in inexpensive AAT diagnostics, understanding of drug resistance, and the effective use of trypanocides in the field. Without this important knowledge it is difficult to develop best practice and policy for existing drugs or to inform development and use of new drugs. There needs to be better understanding of the drivers and behavioural practices around trypanocide use so that they can be incorporated into sustainable solutions needed for the development of effective control of AAT.
Item Type: | Articles |
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Additional Information: | This work was funded by a Biotechnology and Biological Sciences Research Council (BBSRC) grant ( BB/S001034/1 ; BB/S00243X/1 ; BB/S000143/2 ) and the Global Alliance for Livestock Veterinary Medicine (GALVmed), with funding from Bill and Melinda Gates Foundation (BMGF) and UKAID grant ( OPP-1093639 ). M.P.B. is part of the Wellcome Centre for Integrative Parasitology (104111/Z/14/Z). The Roslin Institute (L.J.M.) is funded by the BBSRC ( BBS/E/D/20002173 ). |
Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Richards, Dr Shauna and Auty, Harriet and Morrison, Dr Liam and Barrett, Professor Michael |
Authors: | Richards, S., Morrison, L. J., Torr, S. J., Barrett, M. P., Manangwa, O., Mramba, F., and Auty, H. |
College/School: | College of Medical Veterinary and Life Sciences > School of Infection & Immunity College of Medical Veterinary and Life Sciences > School of Biodiversity, One Health & Veterinary Medicine |
Journal Name: | Trends in Parasitology |
Publisher: | Elsevier (Cell Press) |
ISSN: | 1471-4922 |
ISSN (Online): | 1471-5007 |
Published Online: | 04 May 2021 |
Copyright Holders: | Copyright © 2021 The Authors |
First Published: | First published in Trends in Parasitology 37(9): 831-843 |
Publisher Policy: | Reproduced under a Creative Commons License |
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