Davydov, I., Woods, D., Safiran, Y., Oberoi, P., Fearnhead, O., Fang, S., Jensen, J., Weissman, A., Kenten, J. and Vousden, K. (2004) Assay for ubiquitin ligase activity: High-throughput screen for inhibitors of HDM2. Journal of Biomolecular Screening, 9(8), pp. 695-703. (doi: 10.1177/1087057104267956)
Full text not currently available from Enlighten.
Abstract
An assay for the autoubiquitination activity of the E3 ligase HDM2 (Mdm2) was developed and adapted to a high-throughput format to identify inhibitors of this activity. The assay can also be used to measure the activity of other E3s and may be useful in finding both inhibitors and activators of a wide range of different ubiquitin ligases
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Vousden, Karen |
| Authors: | Davydov, I., Woods, D., Safiran, Y., Oberoi, P., Fearnhead, O., Fang, S., Jensen, J., Weissman, A., Kenten, J., and Vousden, K. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Cancer Sciences |
| Journal Name: | Journal of Biomolecular Screening |
| ISSN: | 1087-0571 |
University Staff: Request a correction | Enlighten Editors: Update this record
Altmetric
Altmetric