Lessons learned and paths forward for rabies dog vaccination in Madagascar: a case study of pilot vaccination campaigns in Moramanga District

Filla, C. et al. (2021) Lessons learned and paths forward for rabies dog vaccination in Madagascar: a case study of pilot vaccination campaigns in Moramanga District. Tropical Medicine and Infectious Disease, 6(2), 48. (doi: 10.3390/tropicalmed6020048) (PMID:33921499) (PMCID:PMC8167587)

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Canine rabies causes an estimated 60,000 human deaths per year, but these deaths are preventable through post-exposure prophylaxis of people and vaccination of domestic dogs. Dog vaccination campaigns targeting 70% of the population are effective at interrupting transmission. Here, we report on lessons learned during pilot dog vaccination campaigns in the Moramanga District of Madagascar. We compare two different vaccination strategies: a volunteer-driven effort to vaccinate dogs in two communes using static point vaccination and continuous vaccination as part of routine veterinary services. We used dog age data from the campaigns to estimate key demographic parameters and to simulate different vaccination strategies. Overall, we found that dog vaccination was feasible and that most dogs were accessible to vaccination. The static-point campaign achieved higher coverage but required more resources and had a limited geographic scope compared to the continuous delivery campaign. Our modeling results suggest that targeting puppies through community-based vaccination efforts could improve coverage. We found that mass dog vaccination is feasible and can achieve high coverage in Madagascar; however, context-specific strategies and an investment in dog vaccination as a public good will be required to move the country towards elimination.

Item Type:Articles
Keywords:Canine rabies, mass dog vaccination, central point vaccination, puppy vaccination, Zeroby30.
Glasgow Author(s) Enlighten ID:Hampson, Professor Katie
Creator Roles:
Hampson, K.Methodology, Supervision, Writing – review and editing
Authors: Filla, C., Rajeev, M., Randriana, Z., Hanitriniana, C., Rafaliarison, R. R., Edosoa, G. T., Andriamananjara, M., Razafindraibe, N. P., Nely, J., Ferreira, A., Yang, A. L., Daniel, F., Clarke, T. A., Farris, Z., Stone, T., Lastdrager, J., Rajaonarivelo, T., Hampson, K., Metcalf, C. J. E., and Valenta, K.
College/School:College of Medical Veterinary and Life Sciences > School of Biodiversity, One Health & Veterinary Medicine
Journal Name:Tropical Medicine and Infectious Disease
ISSN (Online):2414-6366
Published Online:12 April 2021
Copyright Holders:Copyright © 2021 The Authors
First Published:First published in Tropical Medicine and Infectious Disease 6(2): 48
Publisher Policy:Reproduced under a Creative Commons License
Data DOI:10.5281/zenodo.4663084

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
301620The Science of Rabies EliminationKatie HampsonWellcome Trust (WELLCOTR)207569/Z/17/ZInstitute of Biodiversity, Animal Health and Comparative Medicine