TNM staging of foregut (neuro)endocrine tumors: a consensus proposal including a grading system

Rindi, G. et al. (2006) TNM staging of foregut (neuro)endocrine tumors: a consensus proposal including a grading system. Virchows Archiv, 449(4), pp. 395-401. (doi: 10.1007%2Fs00428-006-0250-1)

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Abstract

The need for standards in the management of patients with endocrine tumors of the digestive system prompted the European Neuroendocrine Tumor Society (ENETS) to organize a first Consensus Conference, which was held in Frascati (Rome) and was based on the recently published ENETS guidelines on the diagnosis and treatment of digestive neuroendocrine tumors (NET). Here, we report the tumor–node–metastasis proposal for foregut NETs of the stomach, duodenum, and pancreas that was designed, discussed, and consensually approved at this conference. In addition, we report the proposal for a working formulation for the grading of digestive NETs based on mitotic count and Ki-67 index. This proposal, which needs to be validated, is meant to help clinicians in the stratification, treatment, and follow-up of patients.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:McNicol, Dr Anne-Marie
Authors: Rindi, G., Kloppel, G., Alhman, H., Caplin, M., Couvelard, A., de Herder, W.W., Erikssson, B., Falchetti, A., Falconi, M., Komminoth, P., Korner, M., Lopes, J.M., McNicol, A.M., Nilsson, O., Perren, A., Scarpa, A., Scoazec, J.Y., and Wiedenmann, B.
College/School:College of Medical Veterinary and Life Sciences
Journal Name:Virchows Archiv

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