Osborne, W., Bhandari, S., Tait, R.C. and Franklin, I.M. (2004) Immediate haemostasis with recombinant factor VIIa for haemorrhage following Hickman line insertion in acute myeloid leukaemia. Clinical and Laboratory Haematology, 26(3), pp. 229-231. (doi: 10.1111/j.1365-2257.2004.00604.x) (PMID:15163323)
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Abstract
Bleeding following Hickman line insertion is not uncommon but can be life threatening, especially in the presence of coagulopathy and thrombocytopenia following chemotherapy. Treatment to control the bleeding can be challenging and treatment options are limited. We present our experience of a patient who had persisting haemorrhage immediately following Hickman line insertion for administration of chemotherapy for relapsed acute myeloid leukaemia. Haemostasis could not be achieved after FFP and platelet administration. A single dose of recombinant factor VIIa (rhFVIIa) stopped the bleeding immediately, avoiding the need for surgical intervention or line removal. Our experience indicates rhFVIIa may be an effective option for bleeding related to Hickman line insertion.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Franklin, Prof Ian and Tait, Dr Robert |
| Authors: | Osborne, W., Bhandari, S., Tait, R.C., and Franklin, I.M. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing > Clinical Specialities College of Medical Veterinary and Life Sciences > School of Cardiovascular & Metabolic Health |
| Journal Name: | Clinical and Laboratory Haematology |
| Publisher: | Blackwell Publishing |
| ISSN: | 0141-9854 |
| ISSN (Online): | 1365-2257 |
| Published Online: | 24 May 2004 |
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