Detection of Trypanosoma cruzi in the saliva of diverse neotropical bats

Bergner, L. M. , Becker, D. J., Tello, C., Carrera, J. E. and Streicker, D. G. (2021) Detection of Trypanosoma cruzi in the saliva of diverse neotropical bats. Zoonoses and Public Health, 68(3), pp. 271-276. (doi: 10.1111/zph.12808) (PMID:33484236) (PMCID:PMC8569697)

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Trypanosoma cruzi is widely reported in bats, yet transmission routes remain unclear. We present evidence from metagenomic sequence data that T. cruzi occurs in the saliva of diverse Neotropical bats. Phylogenetic analyses demonstrated that the bat‐associated T. cruzi sequences described here formed part of a bat‐specific clade, suggesting an independent transmission cycle. Our results highlight the value in repurposing metagenomic data generated for viral discovery to reveal insights into the biology of other parasites. Evaluating whether the presence of T. cruzi in the saliva of two hematophagous bat species represents an ecological route for zoonotic transmission of Chagas disease is an interesting avenue for future research.

Item Type:Articles
Glasgow Author(s) Enlighten ID:Streicker, Professor Daniel and Bergner, Dr Laura
Authors: Bergner, L. M., Becker, D. J., Tello, C., Carrera, J. E., and Streicker, D. G.
College/School:College of Medical Veterinary and Life Sciences > School of Biodiversity, One Health & Veterinary Medicine
Journal Name:Zoonoses and Public Health
ISSN (Online):1863-2378
Published Online:23 January 2021
Copyright Holders:Copyright © 2021 The Authors
First Published:First published in Zoonoses and Public Health 68(3): 271-276
Publisher Policy:Reproduced under a Creative Commons licence

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
169793Managing viral emergence at the interface of bats and livestockDaniel StreickerWellcome Trust (WELLCOTR)102507/Z/13/ZRInstitute of Biodiversity, Animal Health and Comparative Medicine