Bahadur, G., Acharya, S. , Muneer, A., Huirne, J., Łukaszuk, M., Doreski, P. A. and Homburg, R. (2020) SARS-CoV-2: diagnostic and design conundrums in the context of male factor infertility. Reproductive BioMedicine Online, 41(3), pp. 3365-369. (doi: 10.1016/j.rbmo.2020.05.014) (PMID:32565229) (PMCID:PMC7267791)
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Abstract
The question of whether SARS-CoV-2 (severe acute respiratory syndrome-related coronavirus-2 [SARS-CoV-2], leading to the COVID-19 infection) can be harboured in the testes and/or semen is currently unanswered. It is essential to understand the limitations of both antibody and real-time PCR tests in interpreting SARS-CoV-2 data in relation to analyses of semen and testicular tissue without appropriate controls. This article critically analyses the evidence so far on this, and the possible implications. The limitations of diagnostic tests in both sampling and testing methodologies, their validation and their relevance in interpreting data are also highlighted.
| Item Type: | Articles |
|---|---|
| Keywords: | COVID-19, diagnosis, infertility, male factor, SARS-CoV-2, semen. |
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Acharya, Santanu |
| Authors: | Bahadur, G., Acharya, S., Muneer, A., Huirne, J., Łukaszuk, M., Doreski, P. A., and Homburg, R. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing |
| Journal Name: | Reproductive BioMedicine Online |
| Publisher: | Elsevier |
| ISSN: | 1472-6483 |
| ISSN (Online): | 1472-6491 |
| Published Online: | 03 June 2020 |
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