Machesky, L. M. and Pollard, T. D. (1993) Profilin as a potential mediator of membrane-cytoskeleton communication. Trends in Cell Biology, 3(11), pp. 381-385. (doi: 10.1016/0962-8924(93)90087-h) (PMID:14731655)
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Abstract
Profilin, the prototype actin-monomer-sequestering protein, has recently emerged as a multifunctional protein with several different activities. Genetic evidence in yeast and flies confirms that profilin is required for a normal actin cytoskeleton, while biochemical evidence suggests a role in regulating phosphoinositide signalling. New studies suggest that profilin may interact with other ligands, and even its role in regulating actin polymerization is now being re-evaluated.
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Machesky, Professor Laura |
Authors: | Machesky, L. M., and Pollard, T. D. |
College/School: | College of Medical Veterinary and Life Sciences > School of Cancer Sciences |
Journal Name: | Trends in Cell Biology |
Publisher: | Elsevier |
ISSN: | 0962-8924 |
ISSN (Online): | 1879-3088 |
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