Heart Failure Association of the European Society of Cardiology update on sodium glucose co‐transporter‐2 inhibitors in heart failure (an update on the Sodium–glucose co‐transporter 2 inhibitors in heart failure: beyond glycaemic control. The position paper of the Heart Failure Association of the European Society of Cardiology)

Seferović, P. M. et al. (2020) Heart Failure Association of the European Society of Cardiology update on sodium glucose co‐transporter‐2 inhibitors in heart failure (an update on the Sodium–glucose co‐transporter 2 inhibitors in heart failure: beyond glycaemic control. The position paper of the Heart Failure Association of the European Society of Cardiology). European Journal of Heart Failure, 22(11), pp. 1984-1986. (doi: 10.1002/ejhf.2026) (PMID:33068051)

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Abstract

The Heart Failure Association (HFA) of the European Society of Cardiology (ESC) has recently issued a position paper on the role of sodium‐glucose co‐transporter 2 (SGLT2) inhibitors in heart failure (HF). The present document provides an update of the position paper, based of new clinical trial evidence. Accordingly, the following recommendations are given: Canagliflozin, dapagliflozin empagliflozin, or ertugliflozin have consistently demonstrated to be effective for the prevention of HF hospitalisation in patients with T2DM and established CV disease or at high CV risk. The specifically listed agents are recommended. Dapagliflozin or empagliflozin are recommended to reduce the combined risk of HF hospitalisation and CV death in symptomatic patients with HF and reduced ejection fraction, already receiving guideline directed medical therapy, regardless of the presence of T2DM.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Jhund, Dr Pardeep and Petrie, Professor Mark
Authors: Seferović, P. M., Fragasso, G., Petrie, M., Mullens, W., Ferrari, R., Thum, T., Bauersachs, J., Anker, S. D., Ray, R., Çavuşoğlu, Y., Polovina, M., Metra, M., Ambrosio, G., Prasad, K., Seferović, J., Jhund, P. S., Dattilo, G., Čelutkiene, J., Piepoli, M., Moura, B., Chioncel, O., Ben Gal, T., Heymans, S., Jaarsma, T., Hill, L., Lopatin, Y., Lyon, A. R., Ponikowski, P., Lainščak, M., Jankowska, E., Mueller, C., Cosentino, F., Lund, L. H., Filippatos, G. S., Ruschitzka, F., Coats, A. J.S., and Rosano, G. M.C.
College/School:College of Medical Veterinary and Life Sciences > Institute of Cardiovascular and Medical Sciences
Journal Name:European Journal of Heart Failure
Publisher:Wiley
ISSN:1388-9842
ISSN (Online):1879-0844
Published Online:17 October 2020
Copyright Holders:Copyright © 2020 European Society of Cardiology
First Published:First published in European Journal of Heart Failure 22(11): 1984-1986
Publisher Policy:Reproduced in accordance with the publisher copyright policy

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