Morrison, P.D., Allardyce, J. and Mckane, J.P. (2002) Fear knot - Neurobiological disruption of long-term fear memory. British Journal of Psychiatry, 180, pp. 195-197. (doi: 10.1192/bjp.180.3.195)
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Abstract
Research in the neurosciences offers valuable insights for psychiatry. Recent animal work qualifies the well-established consolidation hypothesis and suggests long-term memories may be vulnerable to disruption. Following memory reactivation, molecular manipulation of the neuronal systems within a critical time window may result in loss of previously consolidated learned behaviours. An improved understanding of the neurobiology of memory should lead to the improved ability to treat and prevent traumatic memories. Here, we focus on the vulnerability of amygdala-encoded fear memory, although hippocampus-dependent memories also appear susceptible to disruption.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | UNSPECIFIED |
| Authors: | Morrison, P.D., Allardyce, J., and Mckane, J.P. |
| College/School: | College of Medical Veterinary and Life Sciences |
| Journal Name: | British Journal of Psychiatry |
| ISSN: | 0007-1250 |
| ISSN (Online): | 1472-1465 |
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