The sweet side of dark chocolate for chronic kidney disease patients

Fanton, S., Cardozo, L. F.M.F., Combet, E. , Shiels, P. G. , Stenvinkel, P., Vieira, I. O., Narciso, H. R., Schmitz, J. and Mafra, D. (2021) The sweet side of dark chocolate for chronic kidney disease patients. Clinical Nutrition, 40(1), pp. 15-26. (doi: 10.1016/j.clnu.2020.06.039) (PMID:32718711)

Abstract

Chocolate is a widely appreciated foodstuff with historical appreciation as a food from the gods. In addition to its highly palatable taste, it is a rich source of (poly)phenolics, which have several proposed salutogenic effects, including neuroprotective anti-inflammatory, anti-oxidant and cardioprotective capabilities. Despite the known benefits of this ancient foodstuff, there is a paucity of information on the effects of chocolate on in the context of chronic kidney disease (CKD). This review focusses on the potential salutogenic contribution of chocolate intake, to mitigate inflammatory and oxidative burden in CKD, its potential, for cardiovascular protection and on the maintenance of diversity in gut microbiota, as well as clinical perspectives, on regular chocolate intake by CKD patients.

• Item Type: Articles
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Combet Aspray, Professor Emilie and Shiels, Professor Paul
• Authors: Fanton, S., Cardozo, L. F.M.F., Combet, E., Shiels, P. G., Stenvinkel, P., Vieira, I. O., Narciso, H. R., Schmitz, J., and Mafra, D.
• College/School: College of Medical Veterinary and Life Sciences > School of Cancer Sciences; College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing
• Journal Name: Clinical Nutrition
• Publisher: Elsevier
• ISSN: 0261-5614
• ISSN (Online): 1532-1983
• Published Online: 14 July 2020
• Copyright Holders: Copyright © 2020 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism
• First Published: First published in Clinical Nutrition 40(1): 15-26
• Publisher Policy: Reproduced in accordance with the publisher copyright policy